
产品货号:
Z14184
中文名称:
Cortactin/CTTN抗体
英文名称:
Anti-Cortactin/CTTN Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Cortactin/CTTN Antibody |
指标别名 | Amplaxin;cortactin;CTTN;EMS1;Oncogene EMS1;Src substrate cortactin |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,IHC-F,IF,ICC,FCM,ELISA |
基因名称 | CTTN |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human Cortactin recombinant protein (Position:M1-Q105). |
实际分子量 | 61~85KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Cortactin,mapped to 11q13.3,is a multidomain protein.This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck.The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts.This gene has two roles:(1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells.During apoptosis,the encoded protein is degraded in a caspase-dependent manner.The aberrant regulation of this gene contributes to tumor cell invasion and metastasis.Three splice variants that encode different isoforms have been identified for this gene. |
Uniprot ID | Q14247 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 Immunohistochemistry in frozen section 1:50~400 Immunocytochemistry in fixed cells 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells Immunohistochemistry in paraffin section (IHC) 1:50~400 (ELISA): 1:100~1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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